YOU have the Power to
Improve Outcomes.
For chronic wounds that have not progressed appropriately at 4 weeks, it’s TIME TO STEP UP to advanced therapies.
%
DFUs that achieve less than 50% area reduction after 4 weeks of standard of care (SOC) are unlikely to close without escalation.1
Clinical evidence shows these DFUs have only a 9% chance of closure by week 12 with SOC alone.1
MIMEDX human placental allografts provide a protective barrier on wounds and thereby support development of granulation tissue and the healing process.
When Healing Fails to Progress – Risk Accelerates
Non-healing diabetic foot ulcers (DFUs) account for nearly 85% of non-traumatic lower extremity amputations.2
Stalled wounds have a significantly increased risk of infection and the consequences are devastating.3
More likely to be
HOSPITALIZED3
with a stalled wound.
More likely to have an
AMPUTATION3
with a stalled wound.
MIMEDX is Your Proven Partner.
Our advanced wound solutions have demonstrated proven efficacy in 9 randomized controlled trials.
The 4-week assessment helps determine your next step.
MIMEDX provides reimbursement guidance, hands-on education, and clinical resources to help wound care teams navigate the STEP-UP decision.
Resources
Time’s Up Step Up Brochure
Large and Challenging Wounds Brochure
Lyophilized Human Amnion Chorion Membrane (LHACM) Clinical Study: Interim Results Summary
EPIXPRESS Case Study: DFU
EPIXPRESS Case Study: VLU
EPIXPRESS Case Study: Open Trans Metatarsal Amputation
How can we help you?
References
- Sheehan, et al. Diabetes Care. 2003;26(6)
- Clegg DJ, et al. Plast Reconstr Surg Glob Open. 2023;11(11):e5383
- Lavery, et al. Diabetes Care. 2006;29(6):1288-1293






