MIMEDX offers an array of advanced placental-based allografts that may be used in a variety of dermatological applications.
Product Advantages
- Provides a protective barrier that supports the healing cascade
- Protects the wound bed to aid in the development of granulation tissue
- Provides a biocompatible human extracellular matrix (ECM)
- EPIFIX and EPIEFFECT contain 300+ regulatory proteins1-3
- EPICORD contains 250+ regulatory proteins3-4
- Easy to apply
- Shelf-stable* with a 5-year shelf life
Clinical Areas of Use
- Patients who are not good candidates for skin grafts or flaps
- Incisional repair options are limited
- Cosmetically sensitive areas
PEER REVIEWED RETROSPECTIVE STUDY IN FACIAL PLASTIC SURGERY & AESTHETIC MEDICINE5
This study is the first to compare the outcomes of placental allografts with skin grafts and flaps in the management of complex MMS.
Below are the results of a case-control comparison between placental-based allografts and autologous flap/FTSG treatment.
CONCLUSION
Placental-based allografts were helpful in supporting closure for MMS defects of the face, head, neck, and dorsal hand in a subset of patients who were not good candidates for traditional methods of autologous tissue reconstruction.
KEY CHALLENGES
Many factors may complicate healing in Mohs procedures and other dermal excisions and closures.
Patient Factors
- Thin Skin
- Poor Vascularture/Tissue Quality
- Advanced Age
- Comorbidities
Location
- Scalp
- Ears
- Face/Visible Areas
- Shin or Lower Extremity
- Dorsal Hand
Options For EPIFIX Use
- Secondary intention wound closure
- An alternative for patients that are not candidates for skin grafts or flaps
- Location of wound in high tension area or highly visible
- Patients who decline surgery
CASE EXAMPLES
Basal Cell Carcinoma of the Left Antihelix and Scaphoid Fossa6
Invasive Melanoma of the Right Cheek and Lower Eyelid6
Squamous Cell Cancer (SCC) on the Right Pre-Tibial Area7
Basal Cell Carcinoma of the Forehead and Frontal Scalp7
REIMBURSEMENT PROGRAMS COMMITTED TO THE SUCCESS OF YOUR TEAM
- 20+ Field Reimbursement Managers
- 20+ Insurance Verification (IVR) Specialists
- Flexible Options for IVR Submission
- Claims Review
- Appeals Support
- Obtain Health Plan Eligibility, Benefits, and Authorizations
- Available for On-Demand Education
PHYSICIAN TESTIMONIALS
ASHISH BHATIA, M.D., FAAD
ALOK VIJ, M.D., FAAD, FACMS
WEBINARS
Placental-Based Allografts and Mohs Surgery: A Valuable Tool for a Subset of Patients – Dr. Neil Swanson and Dr. Alok Vij
Mohs Surgery & Placental-Based Allografts – Dr. John Adams
BROCHURES
Mohs Surgery
Casebook
Mohs Patient
Brochure
Mohs Study
Overview Brochure
PATIENT TESTIMONIAL
Cynthia’s physician performed Mohs surgery to remove her skin cancer. He applied EPIFIX to the area to help support the wound healing cascade.
CARING FOR CHALLENGING CLOSURES WHEN PATIENTS NEED IT MOST.
*See instructions for Use
References
- Koob TJ, et al. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353-1362.
- Lei J, et al. Adv Wound Care (New Rochelle). 2017;6(2):43-53.
- MIMEDX Internal Report. MM-RD-00086.
- Bullard JD, et al. J Biomed Mater Res B Appl Biomater. 2019;107(4):1035-1046.
- Toman J. Facial Plast Surg Aesthet Med. 2022;24(1):48-53.
- Oliver J. Wisco, DO, FAAD, FCMS, Dermatology, Bend, OR.
- Janice Warner, MD, FAAD, FACMS, Dermatology, Austell, GA.