Mohs surgery is considered the gold standard in treating certain types of skin cancer – EPIFIX offers an additional option for challenging closures.

MOHS SURGERY & PLACENTAL-BASED ALLOGRAFTS:

A Review on Patient Selection, Current Evidence, and Documentation

MOHS SURGEON TESTIMONIAL

Ashish Bhatia, M.D., FAAD
Board Certified Dermatologist and Mohs Surgeon

EPIFIX DERMATOLOGIST TESTIMONIAL

Alok Vij, M.D., FAAD, FACMS

WEBINAR

The Use of Placental-Based Allografts in Mohs/Dermatology Patients with Multiple Comorbidities

MIMEDX offers an array of advanced placental-based allografts that may be used in a variety of dermatological applications.

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Product Advantages

  • Provides a protective barrier that supports the healing cascade
  • Protects the wound bed to aid in the development of granulation tissue
  • Provides a biocompatible human extracellular matrix (ECM)
  • EPIFIX and EPIEFFECT contain 300+ regulatory proteins1-3
  • EPICORD contains 250+ regulatory proteins3-4
  • Easy to apply
  • Shelf-stable* with a 5-year shelf life

Clinical Areas of Use

  • Patients who are not good candidates for skin grafts or flaps
  • Incisional repair options are limited
  • Cosmetically sensitive areas

PEER REVIEWED RETROSPECTIVE STUDY IN FACIAL PLASTIC SURGERY & AESTHETIC MEDICINE5

This study is the first to compare the outcomes of placental allografts with skin grafts and flaps in the management of complex MMS.

Below are the results of a case-control comparison between placental-based allografts and autologous flap/FTSG treatment.

CONCLUSION

Placental-based allografts were helpful in supporting closure for MMS defects of the face, head, neck, and dorsal hand in a subset of patients who were not good candidates for traditional methods of autologous tissue reconstruction. 

KEY CHALLENGES

Many factors may complicate healing in Mohs procedures and other dermal excisions and closures.

Patient Factors

  • Thin Skin
  • Poor Vascularture/Tissue Quality
  • Advanced Age
  • Comorbidities

Location

  • Scalp
  • Ears
  • Face/Visible Areas
  • Shin or Lower Extremity
  • Dorsal Hand

Options For EPIFIX Use

  • Secondary intention wound closure
  • An alternative for patients that are not candidates for skin grafts or flaps
  • Location of wound in high tension area or highly visible
  • Patients who decline surgery

CASE EXAMPLES

Basal Cell Carcinoma of the Left Antihelix and Scaphoid Fossa6

Invasive Melanoma of the Right Cheek and Lower Eyelid6

Squamous Cell Cancer (SCC) on the Right Pre-Tibial Area7

Basal Cell Carcinoma of the Forehead and Frontal Scalp7

REIMBURSEMENT PROGRAMS COMMITTED TO THE SUCCESS OF YOUR TEAM

  • 20+ Field Reimbursement Managers
  • 20+ Insurance Verification (IVR) Specialists
  • Flexible Options for IVR Submission
  • Claims Review
  • Appeals Support
  • Obtain Health Plan Eligibility, Benefits, and Authorizations
  • Available for On-Demand Education

PHYSICIAN TESTIMONIALS

ASHISH BHATIA, M.D., FAAD

ALOK VIJ, M.D., FAAD, FACMS

WEBINARS

Placental-Based Allografts and Mohs Surgery: A Valuable Tool for a Subset of Patients – Dr. Neil Swanson and Dr. Alok Vij

Mohs Surgery & Placental-Based Allografts – Dr. John Adams

BROCHURES

Mohs Surgery
Casebook

Mohs Patient
Brochure

Mohs Study
Overview Brochure

PATIENT TESTIMONIAL

Cynthia’s physician performed Mohs surgery to remove her skin cancer. He applied EPIFIX to the area to help support the wound healing cascade.

CARING FOR CHALLENGING CLOSURES WHEN PATIENTS NEED IT MOST.

Contact us to learn more.

866.477.4219
[email protected]

*See instructions for Use

References
  1. Koob TJ, et al. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353-1362.
  2. Lei J, et al. Adv Wound Care (New Rochelle). 2017;6(2):43-53. 
  3. MIMEDX Internal Report. MM-RD-00086.
  4. Bullard JD, et al. J Biomed Mater Res B Appl Biomater. 2019;107(4):1035-1046.
  5. Toman J. Facial Plast Surg Aesthet Med. 2022;24(1):48-53.
  6. Oliver J. Wisco, DO, FAAD, FCMS, Dermatology, Bend, OR. 
  7. Janice Warner, MD, FAAD, FACMS, Dermatology, Austell, GA.