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Mohs surgery is considered the gold standard in treating certain types of skin cancer – now there's an option for treating challenging closures.

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Mohs surgery is considered the gold standard in treating certain types of skin cancer – now there’s a gold standard for treating challenging closures.

Complimentary Webinar Sponsored by MIMEDX

Mohs Surgery & Placental-Based Allografts:

A review on Patient Selection, Current Evidence, and Documentation

view webinar

> WHY EPIFIX

> PEER-REVIEWED STUDY

> CASE-EXAMPLES

> REIMBURSEMENT

> RESOURCES

EPIFIX® is a dehydrated human amnion/chorion membrane allograft that provides a protective barrier to support the healing cascade.

Product Advantages

  • Protects the wound bed to aid in the development of granulation tissue
  • Provides a biocompatible human extracellular matrix (ECM)
  • Contains 300+ regulatory proteins1-3
  • Easy to apply
  • Shelf-stable* with a 5-year shelf life

Clinical Areas of Use

  • Patients are not good candidates for skin grafts or flaps
  • Incisional repair options are limited
  • An advanced therapy is needed for moderate and high-risk Mohs Micrographic Surgery (MMS) defects in cosmetically sensitive areas

NEW PEER REVIEWED RETROSPECTIVE STUDY IN FACIAL PLASTIC SURGERY & AESTHETIC MEDICINE4

This study is the first to compare the outcomes of placental allografts with skin grafts and flaps in the management of complex MMS.

Below are the results of a case-control comparison between placental-based allografts and autologous flap/FTSG treatment.

CONCLUSION

Placental-based allografts were helpful in supporting closure for MMS defects of the face, head, neck, and dorsal hand in a subset of patients who are not good candidates for traditional methods of autologous tissue reconstruction. 

click here to view study

KEY CHALLENGES

Many factors may complicate healing in Mohs procedures and other dermal excisions and closures.

Patient Factors

  • Thin Skin
  • Poor Vascularture/Tissue Quality
  • Advanced Age
  • Comorbidities

Location

  • Scalp
  • Ears
  • Face/Visible Areas
  • Shin or Lower Extremity
  • Dorsal Hand

Options For EPIFIX Use

  • Secondary intention wound closure
  • An alternative for patients that are not candidates for skin grafts or flaps
  • Location of wound in high tension area or highly visible
  • Patients who decline surgery

CASE EXAMPLES

Basal Cell Carcinoma of the Left Antihelix and Scaphoid Fossa5

Read more

Invasive Melanoma of the Right Cheek and Lower Eyelid5

Read more

Squamous Cell Cancer (SCC) on the Right Pre-Tibial Area6

Read more

Basal Cell Carcinoma of the Forehead and Frontal Scalp5

Read more

REIMBURSEMENT PROGRAMS COMMITTED TO THE SUCCESS OF YOUR TEAM

  • 20+ Field Reimbursement Managers
  • 20+ Insurance Verification (IVR) Specialists
  • Flexible Options for IVR Submission
  • Claims Review
  • Appeals Support
  • Obtain Health Plan Eligibility, Benefits, and Authorizations
  • Available for On-Demand Education
IVR PORTAL
DOWNLOAD HEALTH PROVIDER PATIENT CHECKLIST

WEBINARS

Placental-Based Allografts and Mohs Surgery: A Valuable Tool for a Subset of Patients – Dr. Neil Swanson and Dr. Alok Vij

Mohs Surgery & Placental-Based Allografts – Dr. John Adams

RESOURCES

Mohs Surgery Casebook

download

Mohs Patient Brochure

download

REIMBURSEMENT PROGRAMS COMMITTED TO THE SUCCESS OF YOUR TEAM

Cynthia’s physician performed Mohs surgery to remove her skin cancer. He applied EPIFIX to the area to help support the wound healing cascade.

CARING FOR CHALLENGING CLOSURES WHEN PATIENTS NEED IT MOST.

Contact us to learn more.

866.477.4219
[email protected]

References
  1. Koob TJ, Lim JJ, Massee M, Zabek N, Denozière G. Properties of dehydrated human amnion/chorion composite grafts: Implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353-1362.
  2. Lei J, Priddy LB, Lim JJ, Massee M, Koob TJ. Identification of Extracellular Matrix Components and Biological Factors in Micronized Dehydrated Human Amnion/Chorion Membrane. Adv Wound Care (New Rochelle). 2017;6(2):43-53.
  3. MIMEDX Internal Report. MM-RD-00086, Proteome Characterization of PURION Processed Dehydrated Human Amnion Chorion Membrane (dHACM) and PURION PLUS Processed Dehydrated Human Umbilical Cord (dHUC) Allografts.
  4. Toman J, Michael GM, Wisco OJ, Adams JR, Hubbs BS. Mohs Defect Repair with Dehydrated Human Amnion/Chorion Membrane. Facial Plast Surg Aesthet Med. 2022;24(1):48-53.
  5. Oliver J. Wisco, DO, FAAD, FACMS, Dermatology, Bend, OR.
  6. Janice Warner, MD, FAAD, FACMS, Dermatology, Austell, GA.