Mohs surgery is considered the gold standard in treating certain types of skin cancer – now there's an option for treating challenging closures.
Mohs surgery is considered the gold standard in treating certain types of skin cancer – now there’s a gold standard for treating challenging closures.

Complimentary Webinar Sponsored by MIMEDX
Mohs Surgery & Placental-Based Allografts:
A review on Patient Selection, Current Evidence, and Documentation
> WHY EPIFIX
> PEER-REVIEWED STUDY
> CASE-EXAMPLES
> REIMBURSEMENT
> RESOURCES
Product Advantages
- Protects the wound bed to aid in the development of granulation tissue
- Provides a biocompatible human extracellular matrix (ECM)
- Contains 300+ regulatory proteins1-3
- Easy to apply
- Shelf-stable* with a 5-year shelf life

Clinical Areas of Use
- Patients are not good candidates for skin grafts or flaps
- Incisional repair options are limited
- An advanced therapy is needed for moderate and high-risk Mohs Micrographic Surgery (MMS) defects in cosmetically sensitive areas

NEW PEER REVIEWED RETROSPECTIVE STUDY IN FACIAL PLASTIC SURGERY & AESTHETIC MEDICINE4
This study is the first to compare the outcomes of placental allografts with skin grafts and flaps in the management of complex MMS.
Below are the results of a case-control comparison between placental-based allografts and autologous flap/FTSG treatment.

CONCLUSION
KEY CHALLENGES
Patient Factors
- Thin Skin
- Poor Vascularture/Tissue Quality
- Advanced Age
- Comorbidities
Location
- Scalp
- Ears
- Face/Visible Areas
- Shin or Lower Extremity
- Dorsal Hand

Options For EPIFIX Use
- Secondary intention wound closure
- An alternative for patients that are not candidates for skin grafts or flaps
- Location of wound in high tension area or highly visible
- Patients who decline surgery
CASE EXAMPLES

Basal Cell Carcinoma of the Left Antihelix and Scaphoid Fossa5







REIMBURSEMENT PROGRAMS COMMITTED TO THE SUCCESS OF YOUR TEAM
- 20+ Field Reimbursement Managers
- 20+ Insurance Verification (IVR) Specialists
- Flexible Options for IVR Submission
- Claims Review
- Appeals Support
- Obtain Health Plan Eligibility, Benefits, and Authorizations
- Available for On-Demand Education
WEBINARS
RESOURCES
Mohs Surgery Casebook

Mohs Patient Brochure
CARING FOR CHALLENGING CLOSURES WHEN PATIENTS NEED IT MOST.
References
- Koob TJ, Lim JJ, Massee M, Zabek N, Denozière G. Properties of dehydrated human amnion/chorion composite grafts: Implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353-1362.
- Lei J, Priddy LB, Lim JJ, Massee M, Koob TJ. Identification of Extracellular Matrix Components and Biological Factors in Micronized Dehydrated Human Amnion/Chorion Membrane. Adv Wound Care (New Rochelle). 2017;6(2):43-53.
- MIMEDX Internal Report. MM-RD-00086, Proteome Characterization of PURION Processed Dehydrated Human Amnion Chorion Membrane (dHACM) and PURION PLUS Processed Dehydrated Human Umbilical Cord (dHUC) Allografts.
- Toman J, Michael GM, Wisco OJ, Adams JR, Hubbs BS. Mohs Defect Repair with Dehydrated Human Amnion/Chorion Membrane. Facial Plast Surg Aesthet Med. 2022;24(1):48-53.
- Oliver J. Wisco, DO, FAAD, FACMS, Dermatology, Bend, OR.
- Janice Warner, MD, FAAD, FACMS, Dermatology, Austell, GA.