Proven Applications For Challenging Wounds

Diabetic Foot Ulcer (DFU): EPIFIX + NPWT

EPIFIX used as a protective barrier in a neuropathic diabetic patient. The totality of care avoided a scheduled amputation.

Comorbidities: DM and neuropathy

Goal: Secondary Intention Wound Closure

Patient presented with osteomyelitis and underlying purulent tissue

Post-Debridement + NPWT initiated

Week 8: First EPIFIX application after insurance coverage was received

Week 15: Wound closed, s/p 4 total EPIFIX applications

Exposed Achilles Tendon: EPIFIX

84-year old male with multiple comorbidities and exposed Achilles tendon. Patient had 20 years of steroid use and prior closure attempts including biologic treatments which had failed one year prior to presentation. One week after initial debridement, no granulation tissue was present, so EPIFIX was applied as a protective barrier.

Comorbidities: PVD and pyoderma

Risk Factor: 20 years of steroid use and one year history of failed prior closure attempts

Goal: Bridge to STSG

Initial examination

Week 6: s/p one EPIFIX application. Healthy granulation prep for STSG

Week 16: STSG mostly closed except small area above grafted area

Week 22: Wound closed and stable

Venous Leg Ulcer (VLU): EPIFIX + NPWT

EPIFIX + NPWT in a comorbid patient with 3-year old chronic VLU that failed multiple treatments (e.g., HBOT, skin substitutes, biologics and two skin graft attempts with NPWT).

Comorbidities: DM, CVI and HTN

Goal: Secondary Intention Wound Closure

Week 1: s/p debridement EPIFIX + NPWT

Week 2

Week 3

Day 35: Wound stable at 3, 6, and 12 Month follow-ups