Solutions for Burn Patients
Advanced Placental-Based Allografts When Patients Need It Most
- A semi-permeable protective barrier that supports the healing cascade
- Protects the wound bed to aid in the development of granulation tissue
- Provides a human biocompatible extracellular matrix
Retains Regulatory Proteins
Contains 300+ regulatory proteins1-3
- SMR2T™ Technology and patented PURION processing
- Terminally sterilized for additional level of safety
- Easy to apply
- Room temperature storage
- 5-year shelf life
- Compatible with negative pressure wound therapy (NPWT) and hyperbaric oxygen therapy (HBO)
Potential Clinical Areas of Use
- Points of articulation
- Bone & tendon
Case Study 1:
Full-Thickness Hand Burns to Fingers Bilaterally Treated with DHACM4*
*This case used AMNIOBURN DHACM.
Case Study 2:
Superficial Partial-Thickness Facial Burn Treated with DHACM4*
*This case used AMNIOBURN DHACM.
Case Study 3:
Full-Thickness Burn to Limb Treated with Fenestrated DHACM** + NPWT
Fenestrated DHACM + NPWT in comorbid burn patient with 10cm x 15cm laceration on LLE. Surgical debridement included tendon, soft tissue, and periosteum. Comorbidities: Uncontrolled DM, smoking, CAD, PAD, COPD, HTN, asthma, and arthritis. Goal: STSG or Secondary Intention.
**This case used EPIXL FENESTRATED DHACM which was discontinued on 8/27/21.
CAD = coronary artery disease, COPD = chronic obstructive pulmonary disease, DM = diabetes mellitus, HTN = hypertension, LLE = left lower extremity, NPWT = negative pressure wound therapy, STSG = split thickness skin graft
AMNIOBURN Product Sheet
AMNIOBURN is processed using the PURION process, a unique, patented method for placental-based allografts that is in accordance with the American Association of Tissue Banks (AATB) standards. The product is derived from healthy placental tissue via Caesarean sections from live births in the US. The product undergoes active preservation of the extracellular matrix (ECM) and regulatory proteins. Blood contaminants are removed via a proprietary cleansing process. For an additional level of safety, the product is terminally sterilized.
AMNIOBURN is SMR2T Technology (Selective Membrane of Reparative and Reconstructive Tissue) which provides a semi-permeable protective barrier that supports the healing cascade. The product protects the wound bed to aid in the development of granulation tissue and provides a human biocompatible extracellular matrix that retains 300+ regulatory proteins.1-3
Koob TJ, Lim JJ, Massee M, Zabek N, Denozière G. Properties of dehydrated human amnion/chorion composite grafts: Implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353-1362. 2. Lei J, Priddy LB, Lim JJ, Massee M, Koob TJ. Identification of Extracellular Matrix Components and Biological Factors in Micronized Dehydrated Human Amnion/Chorion Membrane. Adv Wound Care (New Rochelle). 2017;6(2):43-53. 3. MM-RD-00086, Proteome Characterization of Purion Processed Dehydrated Human Amnion Chorion Membrane (dHACM) and Purion Plus Processed Dehydrated Human Umbilical Cord (dHUC) Allografts. 4. Ahuja N, Jin R, Powers C, Billi A, Bass K. Dehydrated Human Amnion Chorion Membrane as Treatment for Pediatric Burns. Adv Wound Care (New Rochelle). 2020;9(11):602-611.